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MMP17 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528219

Catalog No. PIPA528219


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Description

Description

PA5-28219 targets MMP17 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-28219 immunogen is recombit fragment corresponding to a region within amino acids 109 and 438 of Human MMP17. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP ft.s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP ft.s in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
Specifications

Specifications

MMP17
Polyclonal
Unconjugated
MMP17
Liquid
MMP17
Recombit fragment corresponding to a region within amino acids 109 and 438 of Human MMP17
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.74 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Q9ULZ9
MT4-MMP, MMP-17, MT-MMP 4, MT4MMP, MTMMP4, matrix metalloproteinase 17 (membrane-inserted), matrix metalloproteinase-17, membrane-type matrix metalloproteinase 4, membrane-type-4 matrix metalloproteinase
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
4326
Documents
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