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MMP19 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA138199

Catalog No. 01-673-906


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Description

Description

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is placenta tissue.

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPa and TIMPs play a significant role in regulating angiogenesis. MMP-19 is the target of autoantibodies in rheumatoid arthritis and SLE.
Specifications

Specifications

MMP19
Polyclonal
PBS with 1% BSA and <0.1% sodium azide; pH 7.6
Q99542
MMP18, RASI-1, MMP-18, MMP-19, matrix metalloproteinase 18, matrix metalloproteinase 19, matrix metalloproteinase RASI, matrix metalloproteinase-18, matrix metalloproteinase-19
Rabbit
IgG
1 mL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
4327
Immunohistochemistry (Paraffin)
Unconjugated
MMP19
Liquid
MMP19
Synthetic peptide from the N-terminus of human MMP-19 protein
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
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