MMP19 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA138199
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is placenta tissue.MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPa and TIMPs play a significant role in regulating angiogenesis. MMP-19 is the target of autoantibodies in rheumatoid arthritis and SLE.
|PBS with 1% BSA and <0.1% sodium azide; pH 7.6|
|MMP18, RASI-1, MMP-18, MMP-19, matrix metalloproteinase 18, matrix metalloproteinase 19, matrix metalloproteinase RASI, matrix metalloproteinase-18, matrix metalloproteinase-19|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Synthetic peptide from the N-terminus of human MMP-19 protein|
|Antigen affinity chromatography|
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