MMP3 Mouse anti-Human, Clone: 1B4, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112893
A suggested positive control for this product is esophageal or gastric tissues.MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.
|PBS with 0.08% sodium azide|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunohistochemistry, Western Blot|
|Synthetic peptide derived from the C-terminus of the human MMP3|
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