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MMP3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527257

Catalog No. PIPA527257


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Description

Description

PA5-27257 targets MMP3 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27257 immunogen is synthetic peptide corresponding to a region within amino acids 214 and 308 of Human MMP3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.
Specifications

Specifications

MMP3
Polyclonal
Unconjugated
MMP3
Liquid
MMP3
Synthetic peptide corresponding to a region within amino acids 214 and 308 of Human MMP3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P08254
CHDS6, MMP-3, SL-1, STMY, STMY1, STR1, matrix metalloproteinase 3 (stromelysin 1, progelatinase), matrix metalloproteinase-3, proteoglycanase, stromelysin-1, transin-1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
4314
Documents
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