MMP3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527257

Catalog No. PIPA527257

Description

PA5-27257 targets MMP3 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27257 immunogen is synthetic peptide corresponding to a region within amino acids 214 and 308 of Human MMP3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.

Specifications

• Antigen: MMP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMP3
• Format: Liquid
• Gene Symbols: MMP3
• Immunogen: Synthetic peptide corresponding to a region within amino acids 214 and 308 of Human MMP3
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P08254
• Gene Alias: CHDS6, MMP-3, SL-1, STMY, STMY1, STR1, matrix metalloproteinase 3 (stromelysin 1, progelatinase), matrix metalloproteinase-3, proteoglycanase, stromelysin-1, transin-1
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Primary or Secondary: Primary
• Gene ID (Entrez): 4314