MMP3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA513196

Catalog No. PIPA513196

Description

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.

Specifications

• Antigen: MMP3
• Classification: Polyclonal
• Gene: MMP3
• Gene Alias: Stromelysin-1 [Precursor]; SL-1; EC 3.4.24.17; Matrix metalloproteinase-3; MMP-3; Transin-1; MMP3; STMY1
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 4314
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: P08254
• Gene Symbols: MMP3
• Immunogen: KLH conjugated synthetic peptide between 298-327 amino acids from the central region of human MMP3
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG