MMP8 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA513198
DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP8 is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
|PBS with 0.09% sodium azide|
|KLH conjugated synthetic peptide between 286-315 amino acids from the central region of human MMP8|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Immunohistochemistry, Western Blot|
|-20° C, Avoid Freeze/Thaw Cycles|
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