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NSE2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520962

Catalog No. PIPA520962


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Description

Description

A suggested positive control is 293 cell lysate. PA5-20962 can be used with blocking peptide PEP-1076.

MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.
Specifications

Specifications

NSE2
Polyclonal
Unconjugated
NSMCE2
Liquid
NSMCE2
A 15 amino acid peptide near the carboxy terminus of human MMS21.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q96MF7, Q91VT1, Q4V8A0
C8orf36, MMS21, NSE2; E3 SUMO-protein ligase NSE2; MMS21 homolog; hMMS21; methyl methanesulfonate sensitivity gene 21; non-SMC element 2 homolog; non-structural maintece of chromosomes element 2 homolog
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
286053, 299957, 68501
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