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anti-Bax, DyLight 350, Clone: 2D2, Novus Biologicals™

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233092UV

Catalog No. NBP233092UV

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Specifications

Specifications

Bax
2D2
ELISA
Purified
BAX
A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.
21 kDa
0.1 ml
Apoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Primary
581
Human, Monkey, Mouse (Negative), Rat (Negative)
ELISA
DyLight 350
50mM Sodium Borate with 0.05% Sodium Azide
apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4
Mouse
IgG1 Kappa
Protein G purified
RUO
Store at 4C in the dark.
Monoclonal
Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
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