anti-Bcl-10, DyLight 488, Clone: BL10/411, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233190G
DescriptionBcl-10 Monoclonal antibody specifically detects Bcl-10 in Human samples. It is validated for ELISA.
|Human BCL10 recombinant protein (epitope aa122-168)|
|50mM Sodium Borate with 0.05% Sodium Azide|
|B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB|
|Protein G purified|
|Store at 4C in the dark.|
|BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.|
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