CD3 epsilon Antibody (APA1/1), DyLight 680, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP130426FR

Catalog No. NBP130426FR

Description

CD3 epsilon Monoclonal specifically detects CD3 epsilon in Human, Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.

Specifications

• Antigen: CD3 epsilon
• Classification: Monoclonal
• Conjugate: DyLight 680
• Gene Alias: CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
• Host Species: Mouse
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1

• Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
• Clone: APA1/1
• Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
• Gene Symbols: CD3E
• Immunogen: Purified human CD3 proteins isolated from thymus
• Quantity: 0.1 mL
• Research Discipline: Adaptive Immunity, Apoptosis, Diabetes Research, Immunology, Innate Immunity, Signal Transduction
• Gene ID (Entrez): 916
• Target Species: Human, Mouse
• Form: Purified

For Research Use Only