CD68/SR-D1 Antibody (SPM130), DyLight 405, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234736V

Catalog No. NBP234736V

Description

CD68/SR-D1 Monoclonal specifically detects CD68/SR-D1 in Human, Feline, Monkey, Rabbit, Canine (Negative), Chicken (Negative), Porcine (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

• Antigen: CD68/SR-D1
• Classification: Monoclonal
• Conjugate: DyLight 405
• Gene Alias: CD68 antigenmacrophage antigen CD68, CD68 molecule, DKFZp686M18236, GP110, macrosialin, SCARD1, scavenger receptor class D, member 1
• Host Species: Mouse
• Molecular Weight of Antigen: 110 kDa
• Quantity: 0.1 mL
• Research Discipline: Cell Biology, Cytokine Research, Immunology, Microglia Markers
• Gene ID (Entrez): 968
• Target Species: Human, Mouse, Rat, Feline, Primate, Canine (Negative), Chicken (Negative), Porcine (Negative)
• Form: Purified

• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: SPM130
• Dilution: Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Symbols: CD68
• Immunogen: This CD68/SR-D1 Antibody (SPM130) was developed against subcellular fraction of human alveolar macrophages
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

For Research Use Only