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anti-CD74, APC, Clone: SPM523, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP234778APC

Catalog No. NBP234778J


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Description

Description

CD74 Monoclonal antibody specifically detects CD74 in Human, Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD74
SPM523
Flow Cytometry
Purified
CD74
SU-DHL-4 lymphoma cells
Protein A purified
RUO
Store at 4C in the dark.
Monoclonal
CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
Flow Cytometry
APC
PBS with 0.05% Sodium Azide
CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated), CD74 molecule, major histocompatibility complex, class II invariant chain, DHLAGgamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, Ii, MHC HLA-DR gamma chain, p33
Mouse
IgG1 Kappa
0.1 ml
Immunology
Primary
972
Human, Mouse
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