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anti-Chromogranin A, PerCP, Clone: SPM553, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP234795PCP

Catalog No. NBP234795P


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Description

Description

Chromogranin A Monoclonal specifically detects Chromogranin A in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

Chromogranin A
Monoclonal
PerCP
betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Mouse
Protein A or G purified
RUO
Primary
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Purified
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
SPM553
Flow Cytometry
CHGA
Recombinant human chromogranin A protein
0.1 mL
Apoptosis, Cancer, Neuronal Cell Markers
1113
Human
IgG1 κ
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Safety and Handling

SDS
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