anti-Mouse Cytokeratin, LMW, PE, Clone: AE1, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233178PE
DescriptionCytokeratin, LMW Monoclonal antibody specifically detects Cytokeratin, LMW in Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit samples. It is validated for Flow Cytometry.
|Human epidermal keratin was used as the immunogen for the Cytokeratin LMW AE1 antibody.|
|Protein G purified|
|Human, Mouse, Rat, Bovine, Canine, Chicken, Other, Primate, Rabbit|
|PBS with 0.05% Sodium Azide|
|Cytokeratin LMW, cytokeratin-1B, keratin 77, keratin, type II cytoskeletal 1b, KRT77, type-II keratin Kb39|
|Store at 4C in the dark.|
|This MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI less than 5.7) and basic (pI less than 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.|
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For Research Use Only