Cytokeratin, LMW Antibody (AE-1), PE, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP233178PE

Catalog No. NBP233178PE

Description

Cytokeratin, LMW Monoclonal specifically detects Cytokeratin, LMW in Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Rabbit, Reptile samples. It is validated for Flow Cytometry.

Specifications

• Antigen: Cytokeratin, LMW
• Classification: Monoclonal
• Conjugate: PE
• Gene Alias: Cytokeratin LMW, cytokeratin-1B, keratin 77, keratin, type II cytoskeletal 1b, KRT77, type-II keratin Kb39
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 374454
• Target Species: Human, Mouse, Rat, Bovine, Canine, Chicken, Other, Primate, Rabbit
• Form: Purified

• Applications: Flow Cytometry
• Clone: AE-1
• Dilution: Flow Cytometry
• Gene Symbols: KRT77
• Immunogen: Human epidermal keratin (Uniprot: Q7Z794)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: This monoclonal antibody recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI, 48, 46, 45, and 40kDa. monoclonal antibody AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

For Research Use Only