Cytokeratin, pan Antibody (SPM115 + SPM116), HRP, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234394H

Catalog No. NBP234394H

Description

Cytokeratin, pan Monoclonal specifically detects Cytokeratin, pan in Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Rabbit samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Cytokeratin, pan
• Classification: Monoclonal
• Conjugate: HRP
• Gene Symbols: KRT1
• Immunogen: This Cytokeratin, pan Antibody (SPM115 + SPM116) was developed against human epidermal keratin.
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE-1/AE-3 is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

• Applications: Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: SPM115 + SPM116
• Dilution: Western Blot, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Host Species: Mouse
• Molecular Weight of Antigen: 50 kDa
• Quantity: 0.1 mL
• Research Discipline: Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction
• Gene ID (Entrez): 3848
• Target Species: Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit
• Form: Purified

For Research Use Only