anti-Mouse Cytokeratin, pan, PE, Clone: SPM115 + SPM116, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234394PE
DescriptionCytokeratin, pan Monoclonal antibody specifically detects Cytokeratin, pan in Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit samples. It is validated for Flow Cytometry.
|SPM115 + SPM116|
|Human epidermal keratin|
|Store at 4C in the dark.|
|Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit|
|PBS with 0.05% Sodium Azide|
|Protein G purified|
|Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE-1/AE-3 is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.|
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For Research Use Only