anti-Mouse DOG1/TMEM16A, Clone: DOG1.1, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP149559
DescriptionDOG1/TMEM16A Monoclonal antibody specifically detects DOG1/TMEM16A in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
|Tissue culture supernatant, containing less than 0.1% sodium azide with Sodium Azide|
|A synthetic peptide of human DOG1 protein.|
|Tissue culture supernatant|
|Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)|
|Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen|
|ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A|
|Store at 4°C.|
|DOG1/TMEM16A is expressed ubiquitously in gastrointestinal stromal tumors irrespective of c-kit or PDGFR alpha mutation status. Reactivity for DOG1/TMEM16A may aid in the diagnosis of gastrointestinal stromal tumors, including PDGFRA mutants that fail to express c-kit antigen, and lead to appropriate treatment with imatinib mesylate, an inhibitor of the c-kit tyrosine kinase.|
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