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anti-EGF R/ErbB1, APC, Clone: GFR450, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233068APC

Catalog No. NBP233068J


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Description

Description

EGFR Monoclonal antibody specifically detects EGFR in Human, Mouse (Negative) samples. It is validated for Flow Cytometry.
Specifications

Specifications

EGFR
GFR450
Flow Cytometry
Purified
EGFR
Recombinant extracellular domain of human EGFR protein
Protein G purified
RUO
Store at 4C in the dark.
Monoclonal
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Flow Cytometry
APC
PBS with 0.05% Sodium Azide
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Mouse
IgG2a Kappa
0.1 ml
Cancer, Cell Biology, Cell Cycle and Replication, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
Primary
1956
Human, Mouse (Negative)
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