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anti-EGF R/ErbB1, Clone: GFR450, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233068

Catalog No. NBP233068

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EGFR Monoclonal antibody specifically detects EGFR in Human, Mouse (Negative) samples. It is validated for Flow Cytometry, Immunoprecipitation, CyTOF-ready, Block/Neutralize.


10 mM PBS with No Preservative
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
IgG2a Kappa
0.1 mg
Cancer, Cell Biology, Cell Cycle and Replication, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
Human, Mouse (Negative)
Flow Cytometry, Immunoprecipitation, Blocking Assay, CyTOF
1.0 mg/mL
Flow Cytometry 0.5-1ug/million cells, Immunoprecipitation 1-2ug/500ug protein lysate, Blocking/Neutralizing, CyTOF-ready
Recombinant extracellular domain of human EGFR protein
Protein G purified
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
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