Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

anti-ER beta/NR3A2, HRP, Clone: ERb455, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233066H

Catalog No. NBP233066H


Add to cart

Description

Description

ER beta/NR3A2 Monoclonal antibody specifically detects ER beta/NR3A2 in Human, Mouse, Rat, Porcine, Equine, Primate, Sheep samples. It is validated for Western Blot, Simple Western, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications

Specifications

ER beta/NR3A2
ERb455
Western Blot, Simple Western, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Purified
ESR2
A recominant protein fragment specific to Estrogen Receptor beta was used as the immunogen for the ERb455 antibody.
Protein G purified
RUO
Store at 4C in the dark.
Monoclonal
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.
Western Blot, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
HRP
PBS with No Preservative
Erb, ER-beta, ESR-BETA, ESTRB, estrogen receptor 2 (ER beta), estrogen receptor beta, estrogen receptor beta 4, NR3A2ESRB, Nuclear receptor subfamily 3 group A member 2
Mouse
IgG2a
0.1 ml
Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Signal Transduction, Transcription Factors and Regulators
Primary
2100
Human, Mouse, Rat, Porcine, Equine, Primate, Sheep
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only