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anti-IFN-gamma/Granzyme B, Clone: GrB-7, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP151746
DescriptionGranzyme B Monoclonal antibody specifically detects Granzyme B in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
|Western Blot 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500|
|The antibody reacts with the 33 kD human serine protease granzyme B.|
|Tissue culture supernatant|
|Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot|
|I ml tissue culture supernatant with 1.0% BSA with 0.1% Sodium Azide|
|C11, CCPI, CGL1, CGL-1, CSPB, CSP-B, CTLA1, CTSGL1, granzyme B, GZMB, HLP, SECT|
|Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.|
|The monoclonal antibody reacts with the 33 kD human serine protease granzyme B. It does not react with human granzyme A. It is used as a marker for NK-cells and activated cytotoxic T-cells (CTL). This protease is localized in cytoplasmic granules and gives a granular staining pattern. Granzyme B is involved in target cell apoptosis during lymphocyte mediated cyto-toxicity. Exocytosis of granzyme containing granules in the cytoplasm of the target cell will lead to induction of DNA fragmentation and apoptosis of the target cell.|
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