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anti-IFN-gamma/Granzyme B, Clone: GrB-7, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP151746

Catalog No. NBP151746



Description

Description

Granzyme B Monoclonal antibody specifically detects Granzyme B in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications

Specifications

Granzyme B
GrB-7
Western Blot 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Supernatant
GZMB
The antibody reacts with the 33 kD human serine protease granzyme B.
Tissue culture supernatant
RUO
Primary
3002
Human
Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Unconjugated
I ml tissue culture supernatant with 1.0% BSA with 0.1% Sodium Azide
C11, CCPI, CGL1, CGL-1, CSPB, CSP-B, CTLA1, CTSGL1, granzyme B, GZMB, HLP, SECT
Mouse
IgG2a
0.25 ml
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Monoclonal
The monoclonal antibody reacts with the 33 kD human serine protease granzyme B. It does not react with human granzyme A. It is used as a marker for NK-cells and activated cytotoxic T-cells (CTL). This protease is localized in cytoplasmic granules and gives a granular staining pattern. Granzyme B is involved in target cell apoptosis during lymphocyte mediated cyto-toxicity. Exocytosis of granzyme containing granules in the cytoplasm of the target cell will lead to induction of DNA fragmentation and apoptosis of the target cell.
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