anti-Insulin, APC, Clone: SPM531, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234780APC
DescriptionInsulin Monoclonal antibody specifically detects Insulin in Human, Rat, Porcine, Bovine, Rabbit samples. It is validated for Flow Cytometry.
|Full length (1-84 amino acid) purified pig insulin, conjugated to KLH|
|Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers|
|Bovine, Human, Porcine, Rabbit, Rat|
|PBS with 0.05% Sodium Azide|
|IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin|
|Protein A purified|
|Store at 4C in the dark.|
|Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.|
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For Research Use Only