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anti-Integrin alpha L/CD11a, Clone: 87-6F9, Novus Biologicals™

Manufacturer:  Novus Biologicals NBP142196

Catalog No. NBP142196

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.



Integrin alpha L/CD11a
Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, CyTOF-ready
The antibody reacts with the CD11a antigen.
Protein A or G purified
Store at 4C. Do not freeze.
CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA-1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180 kD. Part of heterodimer with CD18 (integrin beta-2). A defect in beta-2 expression results in leucocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections. Source: A BALB/c mouse was immunized and SP2/0 cells were used for fusion with splenocytes.
CyTOF, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
No buffer with No Preservative
CD11 antigen-like family member A, CD11a antigen, CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide, integrin alpha-L, integrin gene promoter, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide), Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, lymphocyte function-associated antigen 1
0.1 mg
Adaptive Immunity, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Myeloid Cell Markers, Signal Transduction, Stem Cell Markers
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