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anti-Lactoferrin, Clone: 265-1K1, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP142417

Catalog No. NBP142417


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Description

Description

Lactoferrin Monoclonal antibody specifically detects Lactoferrin in Human, Rat samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Frozen.
Specifications

Specifications

Lactoferrin
265-1K1
Unconjugated
PBS containing 0.1% BSA with 0.02% Sodium Azide
EC 3.4.21, EC 3.4.21.-, GIG12, growth-inhibiting protein 12, HLF2, Lactoferrin, lactotransferrin, LF, neutrophil lactoferrin, talalactoferrin
Mouse
IgG1
0.05 mg
Amino Acids Drugs and other small molecules
Primary
4057
Human, Rat
Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
0.1 mg/mL
Western Blot 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Purified
LTF
The antibody reacts with the Lactoferrin antigen.
Protein A or G purified
RUO
Store at 4C. Do not freeze.
Monoclonal
The monoclonal antibody 265-1K1 reacts with human lactoferrin (LF), an 80 kDa glycoprotein. Lactoferrin was first isolated from human milk and plays an important part in the immune system and helps to fight infections. Lactoferrin promotes the health of the gastro-intestinal system by improving the intestinal microbial balance. In addition, LF can be found in epithelia and most body fluids and secretions. Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration also represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation. Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration also represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation. Lactoferrin also plays a role in signal transduction, immunomodulation and has antiadhesive, anticancer, antiviral activity.
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