anti-MAGE 1, Alexa Fluor 405, Clone: MA454, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233094AF405
DescriptionMAGE 1 Monoclonal antibody specifically detects MAGE 1 in Human, Rat, Canine samples. It is validated for ELISA.
|Human MAGE-A1 full length recombinant protein|
|Apoptosis, Cancer, Melanoma Cell Markers, Tumor Suppressors|
|Human, Rat, Canine|
|Alexa Fluor 405|
|50mM Sodium Borate with 0.05% Sodium Azide|
|Antigen MZ2-E, Cancer/testis antigen 1.1, cancer/testis antigen family 1, member 1, CT1.1melanoma antigen family A 1, MAGE-1 antigen, MAGE1A, MAGE1melanoma antigen MAGE-1, melanoma antigen family A, 1 (directs expression of antigen MZ2-E), melanoma-associated antigen 1, melanoma-associated antigen MZ2-E, MGC9326|
|Protein G purified|
|Store at 4C in the dark.|
|Recognizes a protein of 42-46kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
For Research Use Only