anti-MUC-1, PE, Clone: GP1.4, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233174PE
DescriptionMUC1 Monoclonal antibody specifically detects MUC1 in Human samples. It is validated for Flow Cytometry.
|Human milk fat globule membrane was used as the immunogen for the EMA antibody.|
|Protein G purified|
|Store at 4C in the dark.|
|In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. This MAb reacts with the DTRP epitope in the tandem repeats. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.|
|PBS with 0.05% Sodium Azide|
|Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin|
|Cancer, Cellular Markers, Extracellular Matrix|
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