anti-NF-H, Clone: NF421, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233102
DescriptionNF-H Monoclonal antibody specifically detects NF-H in Human, Mouse, Rat, Porcine, Chicken samples. It is validated for ELISA.
|10 mM PBS with No Preservative|
|200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H|
|Protein G purified|
|Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.|
|This MAb reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.|
|ELISA 1-5ug/ml for coating|
|A recominant protein fragment specific to Neurofilament 200 kD was used as the immunogen for the NF421 antibody.|
|Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience|
|Human, Mouse, Rat, Porcine, Chicken|
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