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anti-NKX2.2, Alexa Fluor 700, Clone: SPM564, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP234799AF700

Catalog No. NBP234799Z


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Description

Description

NKX2.2 Monoclonal antibody specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications

Specifications

NKX2.2
SPM564
Western Blot, Flow Cytometry, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Purified
NKX2-2
Human NKX2.2 recombinant protein
Protein A purified
RUO
Primary
4821
Chicken, Human, Mouse, Rat
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Alexa Fluor 700
50mM Sodium Borate with 0.05% Sodium Azide
Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B
Mouse
IgG2b Kappa
0.1 ml
Store at 4C in the dark.
Monoclonal
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
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