anti-NKX2.2, Clone: NX2/294, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233058
DescriptionNKX2.2 Monoclonal antibody specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples. It is validated for ELISA.
|10 mM PBS with No Preservative|
|Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B|
|Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.|
|Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.|
|ELISA 1-5ug/ml for coating|
|A recominant protein fragment specific to NKX2.2 was used as the immunogen for the NX2/294 antibody.|
|Protein G purified|
|Human, Mouse, Rat, Chicken|
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