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Plasma Cell Antibody (LIV3G11 (7B18)), DyLight 488, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP233162G
Description
Plasma Cell Monoclonal specifically detects Plasma Cell in Human, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.Specifications
Plasma Cell | |
Monoclonal | |
DyLight 488 | |
Plasma | |
Pancreatic cancer related serum mucin was used as the immunogen for the Plasma Cell antibody. | |
0.1 mL | |
Immunology | |
It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This monoclonal antibody superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma | |
Store at 4C in the dark. | |
IgG2a κ |
Immunohistochemistry (Paraffin) | |
LIV3G11 (7B18) | |
Immunohistochemistry-Paraffin | |
Mouse | |
Protein A or G purified | |
RUO | |
Primary | |
Human, Rat (Negative) | |
Purified |
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