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anti-Renal Cell Carcinoma (gp200), DyLight 550, Clone: 66.4.C2 (PN-15), Novus Biologicals™

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233152R

Catalog No. NBP233152R

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Specifications

Specifications

Renal Cell Carcinoma (gp200)
66.4.C2 (PN-15)
ELISA
Purified
LY75
Fresh, normal human renal cortical tissue homogenate was used as immunogen to generate the RCC antibody.
Protein G purified
RUO
Store at 4C in the dark.
Monoclonal
Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
ELISA
DyLight 550
50mM Sodium Borate with 0.05% Sodium Azide
CD205LY-75, CLEC13BLy-75, C-type lectin domain family 13 member B, DEC-205CD205 antigen, GP200-MR6, lymphocyte antigen 75
Mouse
IgG2b Kappa
0.1 ml
Dendritic Cell Markers, Ovarian Carcinoma Cell Markers, Renal Cell Carcinoma Cell Markers, Vision
Primary
4065
Human, Equine
Documents
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