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anti-TAG-72, Alexa Fluor 405, Clone: SPM536, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP234783AF405

Catalog No. NBP234783W


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Description

Description

TAG-72 Monoclonal antibody specifically detects TAG-72 in Human, Rat, Bovine, Canine samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications

Specifications

TAG-72
SPM536
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Purified
Mouse
IgG1 Kappa
Protein A purified
RUO
Primary
182875
Bovine, Canine, Human, Rat
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Alexa Fluor 405
50mM Sodium Borate with 0.05% Sodium Azide
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72
Purified TAG-72 protein
220 kDa
0.1 ml
Store at 4C in the dark.
Monoclonal
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
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