Von Willebrand Factor Antibody (3E2D10 + VWF635), Alexa Fluor™ 405, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234536AF405

Catalog No. NBP234536W

Description

Von Willebrand Factor Monoclonal specifically detects Von Willebrand Factor in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Von Willebrand Factor
• Classification: Monoclonal
• Conjugate: Alexa Fluor 405
• Gene Alias: coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
• Host Species: Mouse
• Molecular Weight of Antigen: 250 kDa
• Quantity: 0.1 mL
• Research Discipline: Cancer
• Gene ID (Entrez): 7450
• Target Species: Human
• Form: Purified

• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: 3E2D10 + VWF635
• Dilution: Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Symbols: VWF
• Immunogen: Recombinant human Von Willebrand Factor fragment spanning around aa 845-949 (exact sequence is proprietary) (Uniprot: P04275 )
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

For Research Use Only