anti-Von Willebrand Factor, APC, Clone: SPM577, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234810APC
DescriptionVon Willebrand Factor Monoclonal antibody specifically detects Von Willebrand Factor in Human samples. It is validated for Flow Cytometry.
|Von Willebrand Factor|
|Recombinant human vWF fragment|
|PBS with 0.05% Sodium Azide|
|coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF|
|Protein A purified|
|Store at 4C in the dark.|
|Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.|
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