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anti-Von Willebrand Factor, DyLight 680, Clone: SPM577, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP234810FR

Catalog No. NBP234810FR


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Description

Description

Von Willebrand Factor Monoclonal antibody specifically detects Von Willebrand Factor in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications

Specifications

Von Willebrand Factor
SPM577
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Purified
VWF
Recombinant human vWF fragment
250 kDa
0.1 ml
Cancer
Primary
7450
Human
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
DyLight 680
50mM Sodium Borate with 0.05% Sodium Azide
coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
Mouse
IgG1 Kappa
Protein A purified
RUO
Store at 4C in the dark.
Monoclonal
Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
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