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MRE11 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA519611

Catalog No. PIPA519611


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Description

Description

Heat mediated antigen retrieval recommended prior to tissue staining. This antibody is predicted to react with mouse and rat based on sequence homology.

MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex. This complex plays a central role in double-strand break repair, DNA recombination, maintece of telomere integrity and meiosis. The complex possesses single-stranded endonuclease activity and double-strand-specific 3 ft.-5 ft. exonuclease activity which are provided by MRE11. RAD50 is required to bind DNA ends and hold them in close proximity. Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.
Specifications

Specifications

Mre11
Polyclonal
Unconjugated
MRE11
Liquid
MRE11
Synthetic peptide conjugated to KLH derived from within residues 600 - 700 of Human Mre11.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 1% BSA and 0.02% sodium azide
P49959
ATLD, HNGS1, MRE11, MRE11B, AT-like disease; DNA recombination and repair protein; MRE11 homolog 1; MRE11 homolog A; double-strand break repair protein MRE11A; endo/exonuclease Mre11; meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
4361
Documents
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