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MRE11 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520870

Catalog No. PIPA520870


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Description

Description

A suggested positive control is rat lung tissue lysate. PA5-20870 can be used with blocking peptide PEP-0984.

MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex. This complex plays a central role in double-strand break repair, DNA recombination, maintece of telomere integrity and meiosis. The complex possesses single-stranded endonuclease activity and double-strand-specific 3 ft.-5 ft. exonuclease activity which are provided by MRE11. RAD50 is required to bind DNA ends and hold them in close proximity. Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.
Specifications

Specifications

MRE11
Polyclonal
Unconjugated
MRE11
Liquid
MRE11, Mre11a
A 14 amino acid peptide from near the amino terminus human MRE11.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P49959, Q61216, Q9JIM0
ATLD, HNGS1, MRE11, MRE11B; AT-like disease; DNA recombination and repair protein; MRE11 homolog 1; MRE11 homolog A; double-strand break repair protein MRE11A; endo/exonuclease Mre11; meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
17535, 4361, 64046
Documents
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