MRGPRX2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen OSR00110W
Reconstitute with 100 µL of distilled water. Centrifuge to remove any insoluble material.Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion.
|whole serum with no preservative|
|Mas-related G-protein coupled receptor member X2, MRGPRX2, MAS-related GPR, member X2|
|Immunohistochemistry, Western Blot|
|A synthetic peptide from the 4th cytoplasmic loop of human Mas-related G-protein coupled receptor member X2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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