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MRP3 Mouse anti-Human, Clone: M3II-21, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA135679

Catalog No. 01-671-085


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Description

Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
Specifications

Specifications

MRP3
Monoclonal
Unconjugated
ABCC3
Liquid
ABCC3
MRP3.
1 mL
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
8714
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
M3II-21
tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
O15438
ABCC3
Mouse
IgG2b
RUO
Antibody
Monoclonal
Human
Documents
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