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MilliporeSigma™ anti-MSH2 (Ab-3), Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ PC57100UG

Catalog No. PC57100UG


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Description

Description

Specifically detects MSH2 Clone: in Human, Mouse samples, and it is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immuno Blotting

The MSH2 gene is one of at least 4 genes encoding proteins involved in the repair of mismatch nucleotides following DNA replication or repair. Mutations in the MSH2 gene contribute to the development of sporadic colorectal carcinoma, while germline MSH2 mutations are responsible for approximately 50% of inherited, non-polyposis colorectal carcinoma (HNPCC). MSH2 encodes a protein of 934 amino acids.
Specifications

Specifications

MSH2
Unconjugated
purified
full length
100μg
−20°C
Polyclonal
Human, Murine
Immuno Blotting, Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
In 0.05M sodium phosphate buffer, 50% glycerol.
Rabbit
IgG
RUO
Primary
Recognizes the ∽100kDa MSH2 protein in HCT116 and SW480 cells and in colon tissue.
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