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MSH6 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA131302

Catalog No. PIPA131302


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Description

Description

PA1-31302 detects MSH6 from human samples. PA1-31302 has been successfully used in immunoprecipitation, Western blot applications. The PA1-31302 immunogen corresponds to a region between residue 1300 and the C-terminus (residue 1360) of human MutS homolog 6 using the numbering given in entry NP_0001701. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage, and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced maligt transformation and hence the prevention of skin cancer.
Specifications

Specifications

MSH6
Polyclonal
Unconjugated
MSH6
Liquid
MSH6
The epitope recognized by this antibody maps to a region between residue 1300 and the C-terminus (residue 1360) of human MutS homolog 6 using the numbering given in entry NP_0001701
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
1.4 mg/mL
0.01M PBS with 15mM sodium azide; pH 7.2
P52701
GTBP, HNPCC5, HSAP
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2956
Documents
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