MTHFD2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528169
PA5-28169 targets MTHFD2 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-28169 immunogen is recombit fragment corresponding to a region within amino acids 30 and 304 of Human MTHFD2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
|Recombit fragment corresponding to a region within amino acids 30 and 304 of Human MTHFD2|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|NMDMC, NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase, bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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