anti-mTOR Oligoclonal, Invitrogen™
mTOROligoclonal antibody 710408 from Thermo Scientific™ Pierce™ specifically detects mTOR in Human and Rat samples, and it is validated for WB, IF, ICC, FACS and ChIP
Manufacturer: Invitrogen 710408
Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation.
710408 detects mTOR in Human and Rat samples. 710408 has been successfully used in WB, IF, ICC, FACS and ChIP procedures. The immunogen for 710408 is recombinant protein corresponding to amino acids 1126-1411 of human mTOR.
Chromatin Immunoprecipitation, FACS, Immunocytochemistry, Immunofluorescence, Western Blotting
|Store at 2 to 8°C for up to 1 month. For long term storage, store at -20°C.|
|100μg of Protein A antibody in PBS with 0.09% sodium azide;|
|Recombinant protein corresponding to amino acids 1126-1411 of human mTOR.|
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