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TFAM Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527865

Catalog No. PIPA527865


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Description

Description

PA5-27865 targets mtTFA in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27865 immunogen is recombit fragment corresponding to a region within amino acids 1 and 246 of Human mtTFA. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Specifications

Specifications

TFAM
Polyclonal
Unconjugated
TFAM
Liquid
TFAM
Recombit fragment corresponding to a region within amino acids 1 and 246 of Human mtTFA
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Q00059
MtTF1, TCF6, TCF6L1, TCF6L2, TCF6L3, mtTFA, TCF-6, Transcription factor 6-like 2 (mitochondrial transcription factor), mitochondrial transcription factor 1, mitochondrial transcription factor A, transcription factor 6
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
7019
Documents
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