MUSK Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA11741
PA1-1741 detects a predomit band at ~98kD. Other lower MW nonspecific bands of unknown identity were also detected and are likely to be proteolytic fragments.Communication between cells is often mediated by receptors on the surface of the target cell that are triggered by specific ligands released by other cells. Receptor tyrosine kinase activity is strictly regulated by the binding of the appropriate ligand to the extracellular active site of the receptor. These types of receptors play a role critical in the growth and differentiation of different cell types. A muscle specific kinase recently identified, termed MuSK for muscle-specific kinase, and has been shown to be specifically expressed in the muscle cells within the neuromuscular junction. MuSK has been shown to be part of the agrin signaling complex and plays an important role in the development and architectural maintece of the neuromuscular junction.
Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly
|Recombit protein containing residues 210-304 from the extracellular domain of rat MuSK|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide|
|O15146, Q61006, Q62838|
|Nsk3, Mdk4, Nsk2, Nsk1, Mlk, RP23-170A3.1, Muscle-specific kinase receptor, Muscle-specific tyrosine-protein kinase receptor|
|-20° C, Avoid Freeze/Thaw Cycles|
|18198, 4593, 81725|
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