MUTYH Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527855
PA5-27855 targets MUTYH in WB applications and shows reactivity with Human and mouse samples. The PA5-27855 immunogen is recombit fragment corresponding to a region within amino acids 257 and 546 of Human MUTYH. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
|Recombit fragment corresponding to a region within amino acids 257 and 546 of Human MUTYH|
|Antigen affinity chromatography|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|CYP2C, MYH, A/G-specific adenine DNA glycosylase|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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