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MYBPC2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520917

Catalog No. PIPA520917


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Description

Description

A suggested positive control is mouse skeletal muscle tissue lysate. PA5-20917 can be used with blocking peptide PEP-1031.

Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.
Specifications

Specifications

MYBPC2
Polyclonal
Unconjugated
MYBPC2
Liquid
MYBPC2
A 15 amino acid peptide near the carboxy terminus of human MYBPC2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q14324, Q5XKE0
MYBPC, MYBPCF; C-protein, skeletal muscle fast isoform; fast MyBP-C; fast-type muscle myosin-binding-protein C; myosin-binding protein C, fast-type
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
233199, 4606
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