anti-Myelin Basic Protein Polyclonal, Thermo Scientific™

Myelin Basic Protein Polyclonal Ab PA1-10008 from Thermo Scientific™ detects Myelin Basic Protein in Bv, Hu, Ms and Rt samples, and is validated for ICC, IF, IHC and WB

Manufacturer: Invitrogen PA118324

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Catalog No. 01-670-577

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    Specifications

    Antigen Myelin Basic Protein
    Applications Immunohistochemistry
    Conjugate Unlabeled
    Cross Reactivity Human,Rat
    Format Serum
    Formulation 100μL unpurified antibody in whole serum and no preservative
    Gene Accession No. P02686, P02688
    Gene Alias MBP
    Gene Symbols MBP
    Host Species Rabbit
    Immunogen Synthetic peptide corresponding to residues Y(68) G S L P Q K S Q R S Q D E N P V V(86) of guinea pig MBP, conjugated to KLH.
    Isotype IgG
    Quantity 100μL
    Species Reactivity Human, Rat
    Storage Requirements Avoid Freeze/Thaw Cycles
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 24547, 4155

    Myelin Basic Protein Polyclonal Ab PA1-10008 from Thermo Scientific™ detects Myelin Basic Protein in Bv, Hu, Ms and Rt samples, and is validated for ICC, IF, IHC and WB

    Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein. MBP is an 'intrinsically unstructured' protein with a high proportion (approximately 75%) of random coil, but postulated to have core elements of beta-sheet and alpha-helix. MBP is a major protein in CNS myelin and is expressed specifically in the nervous system.
    Host Species: Rabbit
    Cross Reactivity: Human, Rat
    Isotype: IgG
    Immunogen: Synthetic peptide corresponding to residues Y(68) G S L P Q K S Q R S Q D E N P V V(86) of guinea pig MBP, conjugated to KLH.
    Formulation: 100µL unpurified antibody in whole serum and no preservative
    Synonyms: MBP
    Uniprot Accession: P02686, P02688
    Entrez GeneID: 24547, 4155
    Gene Symbol: MBP
    PA1-18324 detects MBP from human and rat samples. PA1-18324 has been successfully used in immunohistochemistry staining of MBP in abnormal oligodendrocytic process and cell bodies in demyelinating areas. This antibody recognizes only areas of myelin degeneration when tested in injured spinal cord and lesioned sciatic nerve, and also stains discrete white matter in the brain of multiple system atrophy. The PA1-18324 immunogen is a synthetic peptide corresponding to residues Y(68) G S L P Q K S Q R S Q D E N P V V(86) of guinea pig MBP, conjugated to KLH. Reconstitute with 100 ul of distilled water.

  • Description & Specifications

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