anti-Myeloperoxidase Polyclonal, Thermo Scientific™

Myeloperoxidase Polyclonal Ab PA1-18308 from Thermo Scientific™ specifically detects Myeloperoxidase in Hu samples, and it is validated for IHC (Paraffin, Frozen) and WB

Manufacturer: Thermo Scientific PA118308

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Catalog No. 01-670-561

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    Specifications

    Antigen Myeloperoxidase
    Applications Immunohistochemistry (Paraffin/Frozen),Western Blotting
    Conjugate Unlabeled
    Cross Reactivity Human
    Format Purified
    Formulation 250μg purified Antibody (1mg/mL) no preservative;
    Gene Accession No. P05164
    Gene Alias MPO
    Gene Symbols MPO
    Host Species Rabbit
    Immunogen Myeloperoxidase isolated from human polymorphonuclear leucocytes.
    Isotype IgG
    Quantity 250μg
    Species Reactivity Human
    Storage Requirements Avoid Freeze/Thaw Cycles
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 4353

    Myeloperoxidase Polyclonal Ab PA1-18308 from Thermo Scientific™ specifically detects Myeloperoxidase in Hu samples, and it is validated for IHC (Paraffin, Frozen) and WB

    Myeloperoxidase is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native Myeloperoxidase is represented as a covalently bound tetrameric complex of two glycosylated alpha chains (MW ~59 - 64 kDa) and two unglycosylated beta chains (MW ~14 kDa) with total MW ~150 kDa and theoretical pI 9.2. Traditionally Myeloperoxidase was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities e.g. periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-Myeloperoxidase autoantibody levels are also reported in rheumatoid arthritis. Recently it was shown that Myeloperoxidase participates in the initiation and progression of cardiovascular disease. It possesses potent proinflammatory properties and may contribute directly to tissue injury. Now Myeloperoxidase is under consideration as one of the most promising cardiac markers.
    Host Species: Rabbit
    Cross Reactivity: Human
    Isotype: IgG
    Immunogen: Myeloperoxidase isolated from human polymorphonuclear leucocytes.
    Formulation: 250µg Purified Antibody (1mg/ml) in Antibody, with no preservative
    Synonyms: MPO
    Uniprot Accession: P05164
    Entrez GeneID: 4353
    Gene Symbol: MPO
    PA1-18308 detects Myeloperoxidase from human samples. PA1-18308 has been successfully used in immunohistochemistry (paraffin and frozen) and Western blot procedures. The PA1-18308 immunogen is Myeloperoxidase isolated from human polymorphonuclear leucocytes. Reconstitute with 250 ul of distilled water.

  • Description & Specifications

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