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Myogenin Mouse anti-Human, Mouse, Rat, Clone: F12B, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA112623

Catalog No. 01-674-007

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

MA1-12623 recognizes a protein of 34 kDa, identified as myogenin. Its epitope localizes between aa 158-178 of myogenin. Myogenin is a member of a family of myogenic regulatory genes, which includes MyoD, myf5 and MRF4. These genes encode a set of transcription factors, which are essential for muscle development. Expression of myogenin is restricted to cells of skeletal muscle origin. It is therefore a useful marker for tumors of the muscle lineage, being strongly expressed in alveolar rhabdomyosarcomas. This antibody can immunoprecipitate protein-DNA complex and is the antibody of choice for staining of formalin-fixed, araffin-embedded tissues.

A suggested positive control for this product is Rhabdomyosarcoma or Wilm's tumors.
Specifications

Specifications

Myogenin
Monoclonal
0.5 mg/mL
Assay Dependent
MYOG
Liquid
MYOG
Recombit protein containing rat myogenin residues 30-224.
Protein A/G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
ELISA, Gel Shift, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
F12B
Unconjugated
PBS with 0.08% sodium azide
P15173, P12979, P20428
MYF4, MYOG
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
17928, 29148, 4656
Documents
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